This page shows the latest Genfit news and features for those working in and with pharma, biotech and healthcare.
As drugmakers race to bring treatments for NASH to market, the therapy area has seen a number of late-stage failures, including Gilead’s ASK1 inhibitor selonsertib and Genfit’s elafibranor.
So far, the success of those efforts has been mixed, with Genfit’s rival Gilead also reporting disappointing late-stage trials of its ASK1 inhibitor selonsertib. ... efforts on our two top priorities: the PBC program and NIS4,” said Pascal Prigent,
Intercept is trailed by Genfit, which is due to release late-phase data on its candidate this quarter, and a large pack of companies with earlier-phase candidates.
French pharma Genfit also has a candidate being studied in NASH in a phase 3 trial, with interim results due in the next few months.
It will enrol patients with suspected NASH and significant to advanced fibrosis, measured using non-invasive diagnostic tools including Genfit’s own NIS4 diagnostic test for NASH. ... Dean Hum. “NASH is a multifaceted cardio-metabolic disease
Elafibranor has shown promising anticholestatic effects in a Phase 2 clinical trial,” said Pascal Birman, Deputy Chief Medical Officer, Genfit. ... Genfit’s drug has been shown to reduce this however, operating as a dual agonist of the peroxisome
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