This page shows the latest GVAX news and features for those working in and with pharma, biotech and healthcare.
The immunotherapy combines CRS-207 - a drug that promotes the expression of the tumour-associated antigen mesothelin - with an immune-boosting GVAX cell line, and is Aduro's lead product candidate. ... Aduro is not giving up on the CRS-207/GVAX vaccine
mechanism of action than the current crop of treatments, as well as Cephalon/Hospira's Omapro (omacetaxine), BioSante Pharma's GVAX and Deciphera's ABL inhibitor rebastinib (DCC-2036).
Vaccines such as CancerVax (Canvaxin), Genitope Corp (MyVax personalised immunotherapy), Favrille Inc (FavId), Therion (Panvac), CG 8123 (Gvax; Cell Genesys) have not been as successful, and development of these vaccines has
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marked more by failures than successes, with a string of candidates (including Aduro’s GVAX, CancerVax’ Canvaxin, and Genitope’s MyVax) missing the mark in late-stage testing.
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