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HER2-negative breast cancer

This page shows the latest HER2-negative breast cancer news and features for those working in and with pharma, biotech and healthcare.

Pfizer and Arvinas announce $1bn deal for investigational oral protein degrader

Pfizer and Arvinas announce $1bn deal for investigational oral protein degrader

ARV-471 is currently in a phase 2 trial for the treatment of patients ER-positive, HER2-negative locally advanced or metastatic breast cancer. ... Pfizer and US biopharma company Arvinas have signed a collaboration agreement to jointly develop and

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  • Leading AstraZeneca’s return to growth in Europe Leading AstraZeneca’s return to growth in Europe

    The drug has so far gained approval for use in patients with germline BRCA1/2-mutated (gBRCAm), human epidermal growth factor receptor 2 (HER2)- negative locally advanced or metastatic breast cancer, ... That’s a measure of its heightened ambitions in

  • The handover: Pfizer reshapes itself for a new era The handover: Pfizer reshapes itself for a new era

    Innovative health revenue increased 4% to $8.47bn, lifted by sales of blood thinner Eliquis and breast cancer drug Ibrance outside the US, among others. ... In October the FDA also approved Talzenna (talazoparib), a new treatment of deleterious or

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