Please login to the form below

Not currently logged in
Email:
Password:

HIF-PHI

This page shows the latest HIF-PHI news and features for those working in and with pharma, biotech and healthcare.

Astellas files new application for expanded use of roxadustat in Japan

Astellas files new application for expanded use of roxadustat in Japan

Roxadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI). In contrast to ESAs, HIF-PIH inhibitors stimulate endogenous production of erythropoietin, the protein on which ESAs are based.

Latest news

  • GSK files anaemia drug daprodustat in Japan, its first market GSK files anaemia drug daprodustat in Japan, its first market

    Daprodustat – a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) – will be distributed in Japan by Kyowa Kirin if it gets the nod from the Ministry of Health, Labour and Welfare ... In contrast, HIF-PHI drugs stimulate endogenous

  • China first market to approve AZ’s kidney drug roxadustat China first market to approve AZ’s kidney drug roxadustat

    Roxadustat is a hypoxia-inducible factor prolyl hydroxylase inhibitor (HIF-PHI) and according to AZ’s chief medical officer Sean Bohen is the first oral drug in this class, as well ... In contrast, HIF-PH inhibitors stimulate endogenous production of

  • GSK starts late-stage trials of daprodustat GSK starts late-stage trials of daprodustat

    CKD). The orally-active hypoxia-inducible prolyl hydroxylase inhibitor (HIF-PHI) could be a $450m product by 2020, according to Credit Suisse forecasts, and is one of a block of new ... administration.". GSK is in a race to market with other HIF-PHI

  • AZ inks $815m deal for FibroGen anaemia drug AZ inks $815m deal for FibroGen anaemia drug

    The drug is an orally administered small molecule inhibitor of hypoxia-inducible factor prolyl hydroxylase (HIF-PHI) and offers an alternative to injectable treatments based on erythropoietin (EPO), which account for

More from news
Approximately 1 fully matching, plus 4 partially matching documents found.

Subscribe to our email news alerts

Featured jobs

PMHub

Add my company
Graphite Digital

We’re a digital CX agency collaborating with healthcare and pharmaceutical organisations to help them connect more deeply with their audiences...

Latest intelligence

The communication challenge of helping he next generation to be healthier
As the pressure on the health service increases the health of the next generation is vital for everyone. How do we show positive attitudes and change behaviour while future proofing...
Are we losing sight of what the democratisation of healthcare really looks like?
We have a core responsibility as healthcare communicators to consistently drive for better inclusion, engagement and compliance. What does the ‘democratisation of healthcare’ really look like?...
William Kilgallon
How the Royal Society’s EiR programme can help to drive UK innovation
...