This page shows the latest IDO inhibitor news and features for those working in and with pharma, biotech and healthcare.
Incyte is still trying to recover from the mauling it took after its IDO inhibitor epacadostat for cancer failed earlier this year, and yesterday wrote off another programme in ... JAK1/JAK2 inhibitor Jakafi – given in combination with corticosteroids
IDO1 inhibitor given alongside Opdivo, BMS’ CTLA4 inhibitor Yervoy (ipilimumab), other marketed cancer drugs and LAG-3 candidate relatlimab. ... Meanwhile another study of epacadostat with AstraZeneca’s PD-L1 inhibitor Imfinzi (durvalumab) will also
efforts on its IDO checkpoint inhibitor programme. ... The IDO inhibitor pipeline is currently led by indoximod, which is in phase II for breast cancer (in combination with taxane drugs docetaxel and paclitaxel) and prostate cancer (in combination with
With the addition of a potentially best-in-class IDO1 inhibitor and the broad IDO/TDO programmes, Bristol-Myers Squibb will accelerate its ability to explore numerous immunotherapeutic approaches across tumour ... the development of our potentially
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Meanwhile, despite the mixed results for checkpoint inhibitor combinations to date, there’s no let-up in the pursuit of new cocktail recipes. ... Meanwhile, Incyte’s Merck &Co partnered IDO inhibitor epacadostat bombed when paired with Keytruda in a
F001287, IDO1 inhibitor IDO/TDO discovery programme - immuno-oncology. Corporate acquisition. 1, 250. ... Abbreviations:. IDO, Indoleamine-2, 3-dioxygenase; TDO, Tryptophan-2, 3- dioxygenase. COPD, chronic obstructive pulmonary disease.
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