This page shows the latest linaclotide news and features for those working in and with pharma, biotech and healthcare.
AstraZeneca '. primarily responsible' on commercialisation across the vast country. Tom McCourt, Ironwood's new president said: “Regulatory approval in China represents another important step in bringing linaclotide to millions of adult
Linzess (linaclotide) – which brought in almost $575m in sales for Allergan in the first nine months of the year – works by binding to intestinal epithelial cells and stimulating the secretion of
includes Linzess (linaclotide) for IBS with constipation.
Plecanatide's closest competitor in the market is Ironwood/Allergan's Linzess/Constella (linaclotide), described as a guanylate cyclase stimulant, which is approved for the treatment of constipation-predominant IBS in
Phase III trial of linaclotide show it improved symptoms such as abdominal pain. ... AstraZeneca (AZ) and Ironwood Pharmaceuticals say they are on course to submit irritable bowel syndrome treatment linaclotide for approval in China in early 2016.
sit well in its portfolio alongside constipation-predominant IBS drug Linzess (linaclotide).
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years. Among a newer generation of orally-delivered peptides is Ironwood Pharma's peptide drug Linzess/Constella (linaclotide) - which debuted in 2012 for constipation associated with irritable bowel syndrome.
In addition, Ironwood could receive a further $125m in milestones if certain sales targets for linaclotide are met. ... 153. Ironwood / AstraZeneca. Co-develop &co-commercialise (profit/ loss share). Linaclotide, IBS with constipation (FDA approved).
pulmonary disease (COPD) and linaclotide indicated for irritable bowel syndrome with constipation, for which there is no specific treatment approved by the European Medicines Agency (EMA).
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Owens is a former partner at investments advisor Wellington Management, and joins the US-based biopharma at a time of growth following the approval of Linzess (linaclotide) in the US for
Currie's academic research on the guanylate cyclase-C (GC-C) pathway laid the foundation for the discovery by Ironwood scientists of linaclotide. ... Linaclotide was approved as a treatment for irritable bowel syndrome last year by regulators in Europe,
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