Latest news

• Pfizer’s ALK inhibitor Lorbrena hits the mark in head-to-head lung cancer trial

  Lorbrena (lorlatinib) reduced the risk of disease progression or death by 72% in ALK-positive NSCLC patients compared to Xalkori (crizotinib) in the phase 3 CROWN trial, presented over the weekend

• Pfizer’s Xalkori follow-up Lorbrena hits the mark in first-line lung cancer

  Lorbrena (lorlatinib) is being evaluated in patients with previously untreated ALK-positive non-small cell lung cancer – participants were randomised to receive either Lorbrena monotherapy or Pfizer’s first-generation

• Pfizer’s Talzenna cleared for breast cancer in Europe

  Talzenna is one of four new targeted therapies it is hoping will drive growth in cancer, along with Xalkori follow-up Lorbrena (lorlatinib) in second-line ALK-positive NSCLC, SMO inhibitor

• Pfizer poaches cancer R&D head Jeff Settleman from Calico

  That includes Xalkori follow-up Lorbrena (lorlatinib) for ALK-positive non-small cell lung cancer (NSCLC), PARP inhibitor Talzenna (talazoparib) for breast cancer, Daurismo (glasdegib) for acute myeloid leukaemia, and Vizimpro

• Pfizer gets EU nod for Tagrisso rival Vizimpro

  Last November, the drugmaker claimed FDA approval for Xalkori follow-up Lorbrena (lorlatinib) in second-line ALK-positive NSCLC and SMO inhibitor Daurismo (glasdegib) for acute myeloid leukaemia, while in October