This page shows the latest PAH news and features for those working in and with pharma, biotech and healthcare.
PAH is a rare, progressive and life-threatening blood vessel disorder characterised by the constriction of small pulmonary arteries and elevated blood pressure in the pulmonary circulation, resulting in a significant ... An estimated 500 to 1, 000 new
of-care treatment, with the five-year mortality rate for patients with PAH approximately 43%. ... We believe that in totality, the results observed in the STELLAR study suggest that sotatercept has the potential to transform the treatment of patients
We expect that, by the end of 2022, Acceleron will have results from its phase 3 STELLAR trial that is enrolling the prevalent PAH population, which we believe will support a
2 PULSAR clinical trial in patients with pulmonary arterial hypertension (PAH).
PAH is already a multibillion-dollar market – in 2017, Johnson &Johnson paid $30bn for Swiss drugmaker Actelion including its PAH drugs, while PAH drugs collectively made $1.7bn in worldwide sales ... The FDA has awarded sotatercept breakthrough
The Phearless study was investigating the AAV5-phenylalanine hydroxylase (PAH) gene therapy in adults with phenylketonuria (PKU), a genetic disorder affecting approximately 70, 000 diagnosed patients in the regions of the ... PKU is caused by a
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Most recently at Janssen, we have collaborated with patients and healthcare professionals to create a first-of-its-kind pulmonary arterial hypertension (PAH) Patient Charter, designed to set the baseline for ... holistic PAH care.
For regularly misunderstood rare disease patients, such as those with PAH, this information is critical for developing medicines that may not only improve their prognosis but also their everyday lives. ... PAH treatment strategies or interventions, an
For example, our recent work to design a patient and carer mobile application for PAH has benefited from ongoing collaboration with clinicians, patient advocacy groups and leading tertiary centres across the
Merck &Co grew cardiovascular revenues by 130%, while GSK enjoyed a 214% uplift, mainly due to its PAH treatment Volibris.
In an attempt to be hunter rather than hunted, and to diversify its portfolio from just PAH (pulmonary arterial hypertension), Actelion has acknowledged it is holding “preliminary discussions with ZS Pharma”. ... complement Actelion's PAH portfolio.
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At that point it will gain marketed products that include a trio of pulmonary artery hypertension (PAH) drugs - Tracleer (bosentan), Opsumit (macitentan) and Uptravi (selexipag). ... strong long-term growth potential to achieve leading positions in
Prior to joining Plexxikon, Dr Nolop was VP of clinical research at CoTherix, where he led the development and US approval for Ventavis (iloprost) to treat pulmonary arterial hypertension (PAH).
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Healthcare is evolving rapidly. To stand out from the crowd requires a potent combination of rich insight, innovative ideas and...