This page shows the latest Pruritus news and features for those working in and with pharma, biotech and healthcare.
The most frequently reported adverse drug reactions (ADRs) (> 5%) were pruritus (9.4%), rash (8%), headache (7.2%), urticaria (6.5%), fatigue (6.5%), nausea (5.8%) and chills (5.1%).
Menlo Therapeutics has said its phase 2 trial of serlopitant in chronic itching (pruritus) is a bust, blaming the result on a high placebo response rate. ... It also said the data has no read-through to its lead indication for serlopitant in pruritus
The safety and tolerability profile of obeticholic acid, which is associated with pruritus, may limit the number of patients and physicians who want to use the drug, even if it is
However, the results were far from a home run, as Ocaliva missed a co-primary endpoint of resolving NASH, and more than half of patients on the 25mg dose experience pruritus
pruritus (itching).
The mixed efficacy data, coupled with safety results revealing that more than half of patients on the 25mg dose experienced itching (pruritus) that in 9% was sufficiently severe for them to
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Cara Therapeutics put two questionnaires about itching at the centre of its phase 3 pruritus trial.
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Moukheiber will head the board as it progresses its lead product CT327, a first-in-class selective TrkA kinase inhibitor for the treatment of pruritus (itching) due to psoriasis.
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4. Reich A, et al. Pruritus is an important factor negatively influencing the well-being of psoriatic patients.Acta dermato-venereologica, 2010; 90(3): 257-263.
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