This page shows the latest Sting agonists news and features for those working in and with pharma, biotech and healthcare.
combinations. The STING pathway plays a critical role during infections and autoimmune disease, as well as one of the key innate immunity pathways responsible for antitumour immunity. ... Ryvu’s STING agonists have already shown promising results in
More than a dozen biopharma companies have been looking at STING agonists as potential treatments for cancer by switching on the inflammatory response against tumour cells, including Merck &Co and Novartis. ... There’s still interest in STING agonists,
Terms of the deal haven’t been disclosed. There has been a rush to bring STING agonists forward into clinical trials, in the hope that they could enhance the activity of ... pipeline. Meanwhile, Mavupharma isn’t the only company trying to develop
BMS’ interest was mainly on IFM’s STING and NLRP3 agonists and their potential in boosting immune responses to tumours.
also that the STING agonists were speculated to be more potent based on biology and some preclinical studies. ... Now, they say “the apparent comparable potency between the two classes of agents, a potentially worse safety profile for STING, and the
The collaboration with California-based Aduro is focused on the development of cancer immunotherapies based on the STING (Stimulator of Interferon Genes) receptor that - when activated - is through to initiate a ... On the other hand, Aduro's STING
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There are various companies working on toll-like receptor agonists that stimulate antigen-presenting cells, such as Idera’s TLR9-targeted drug IMO-2125 which boosted the activity of BMS’ CTLA4 ... Among the plethora in the pipeline, Aurigene and BMS
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