This page shows the latest tenofovir news and features for those working in and with pharma, biotech and healthcare.
Gilead Sciences (Gilead) has announced that the European Commission (EC) has authorised a new low-dose tablet dosage form of Biktarvy (bictegravir/emtricitabine/tenofovir alafenamide) and an extension of its indication
Gilead Sciences (Gilead) supplemental new drug application (sNDA) for Vemlidy (tenofovir alafenamide) 25mg tablets to treat chronic hepatitis B virus (HBV) infection in paediatric patients 12 years and older with compensated
The studies demonstrated that cabotegravir long-acting for PrEP was superior to daily oral emtricitabine/tenofovir disoproxil fumarate (FTC/TDF), with clinical trial participants experiencing a 69% lower rate of HIV
which highlighted Biktarvy (bictegravir 50mg/emtricitabine 200mg/tenofovir alafenamide 25mg tablets, B/F/TAF) as a generally well-tolerated and efficacious regimen, regardless of prior treatment and comorbidity status in people
Without the Veklury bump, total product sales decreased by 3% to $5.4bn for the third quarter, primarily due to the loss of exclusivity of HIV combination therapies Truvada (emtricitabine/tenofovir ... The drop was also partially offset by a 20% increase
However, total product sales excluding Veklury dropped by 11% to $4.9bn compared to Q1 2020, due to the loss of exclusivity of its HIV drugs Truvada, tenofovir disoproxil fumarate and
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With Triumeq signalling the approval of the first STR without tenofovir disoproxil fumarate (TDF) it can, uniquely, be used in those patients with impaired kidney function. ... Gilead, in hot pursuit, is in phase III of development of a new regimen where
Merck has licensed CMX 157 an oral nucleoside reverse transcriptase inhibitor for treatment of HIV that is 200-fold more potent in vitro than tenofovir (Gilead's product with sales of
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10. Tenofovir – a nucleotide reverse transcriptase inhibitor (NtRTI). 11. Acts as a nucleotide analogue that competitively inhibits reverse transcriptase, the enzyme required for replication of the viral genome.
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