This page shows the latest Torisel news and features for those working in and with pharma, biotech and healthcare.
The FDA notes that Opdivo is the first drug to show an improvement in overall survival in RCC since Novartis' Torisel (temsirolimus), which was approved in 2007.
Several mTOR antagonists have already been launched for different cancers and could therefore be prescribed as off-label therapy; these include everolimus (Zortress/Certican, Novartis), sirolimus (Rapamune, Wyeth) and temsirolimus (Torisel,
Phase I trials are also under way in paediatric patients with recurrent solid tumours, either as a monotherapy or in combination with temsirolimus (Torisel; Pfizer), which is an inhibitor of mTOR,
NICE has approved Pfizer's Sutent as a kidney cancer first line treatment, but turned down Roche's Avastin, Bayer's Nexavar and Wyeth's Torisel. ... The body also turned down Avastin (bevacizumab), Nexavar (sorafenib) and Torisel (temsirolimus), despite
Sutent was originally reviewed along with Roche's Avastin (bevacizumab), Bayer's Nexavar (sorafenib), and Wyeth's Torisel (temsirolimus) as part of a multiple technology appraisal.
The four drugs for advanced kidney cancer – Sutent, Nexavar, Avastin and Torisel – could be released from their ban and made available on the NHS for treatment of advanced kidney cancer patients.
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Mirna will be banking on Dr Kim's extensive experience in oncology, which includes serving as global clinical lead for kidney cancer drugs Inlyta (axitinib) and Torisel (temsirolimus) during his time
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