Imbruvia, a once-daily oral medication jointly developed and commercialised by Janssen Biotech and Pharmacyclics LCC, works by blocking the Bruton's tyrosine kinase (BTK) protein, which is needed by normal
including a $21bn takeover of Pharmacyclics and $9.8bn deal for Stemcentrx.
Analysts have not been overly impressed with the bolt-on acquisitions AbbVie has paid for in recent years; the $21bn it spent acquiring Pharmacyclics and its lymphoma treatment Imbruvica was seen
Bob Duggan. Duggan was chief executive and president of Pharmacyclics when it was sold to AbbVie for $21bn in 2015, immediately catapulting him into the ranks of biotech billionaires, and Summit ... The heady valuation of the Pharmacyclics deal was
The first BTK inhibitor to reach the market was Johnson &Johnson (J&J) and Pharmacyclics' Imbruvica (ibrutinib), but this has been introduced initially for blood cancers including chronic lymphocytic leukaemia (CLL) ... Meanwhile, Pharmacyclics (now part
Wisepress is a medical bookseller promoting and selling books worldwide, both online and via the 200 European medical conferences that...