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PMLiVE Top Pharma List

Pharmacyclics

AZ confirms interest in Acerta takeover

AZ confirms interest in Acerta takeover Acalabrutinib is a Bruton's tyrosine kinase (Btk) inhibitor in the same class as Janssen/Pharmacyclics/Abbvie's Imbruvica (ibrutinib), which is on course to become a $1bn product this year ... Ibrutinib is tipped to become a $5bn-plus product at peak,

Servier announces job cuts as pressures mount

Servier announces job cuts as pressures mount Servier has also had some pipeline setbacks of late. Last year the company abandoned development of its HDAC inhibitor abexinostat for cancer, returning rights to Pharmacyclics, while in October it walked

J&J's share buyback 'doesn't prevent acquisitions'

J&J's share buyback 'doesn't prevent acquisitions' Such a move would be popular with investors who are keen to see the company put that money to good use, particularly after a reported bid for its Imbruvica partner Pharmacyclics

Imbruvica filed as first-line leukaemia therapy

Imbruvica filed as first-line leukaemia therapy Imbruvica is a first-in-class Bruton's tyrosine kinase (BTK) inhibitor - licensed by Janssen from Pharmacyclics in 2011 in a deal valued at up to $975m. ... CLL. The results showed that treatment with J&J and Pharmacyclics' drug improved both

Horizon launches $3bn hostile bid for Depomed

Horizon launches $3bn hostile bid for Depomed Horizon's bid comes as the value of M&A activity in the pharma sector is spiking in the first half of 2015, led by AbbVie's $21bn takeover of Pharmacyclics,

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