The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Gleevec/Glivec was produced by Novartis.
The main case in the latter category - which involves Novartis' leukaemia drug Glivec (imatinib) - has been rumbling on for years and has now reached the level of India's Supreme Court.
Stivarga (regorafenib) has been given the go-ahead by the FDA to treat advanced GIST that cannot be removed surgically and have failed to respond to prior treatment with Novartis' Gleevec ... whose cancer had progressed despite Gleevec and Sutent therapy.
Ruvise (imatinib mesylate) is already available for the treatment of several cancers under the brand name Gleevec/Glivec, but Novartis has hoped to expand the drug's use by submitting it ... Imatinib mesylate is already one of Novartis' biggest earners
Novartis also launched key products, such as cancer treatment Gllevec/Glivec (imatinib) and blood pressure medicine Tekturna (aliskiren), during Dr Vasella's time in charge.
Philadelphia chromosome-positive CML who have previously been treated with tyrosine kinase inhibitor drugs such as Novartis' Glivec/Gleevec (imatinib).
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