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PMLiVE Top Pharma List

29

Revenue 2017

Soliris

The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Soliris was produced by Alexion.

HTA guidance from NICE, the SMC and the AWMSG

16 Apr 2021. NICE said clinical evidence shows Ultomiris is as effective and safe as Alexion's older PNH drug Soliris.

AstraZeneca clears latest hurdle for Alexion acquisition after EU clearance

AstraZeneca clears latest hurdle for Alexion acquisition after EU clearance This includes the company’s complement component 5 (C5) inhibitors Soliris (eculizumab) and Ultomiris (ravulizumab), which are already available in the US and EU.

UK’s Competition and Markets Authority to review AZ/Alexion merger

UK’s Competition and Markets Authority to review AZ/Alexion merger That includes the company’s complement component 5 (C5) inhibitors Soliris (eculizumab) and Ultomiris (ravulizumab), which are already available in the US and the EU. ... programmes. AZ projects that the acquisition will deliver double-digit average

NICE recommends Ultomiris for NHS use in patients with rare blood disorders

NICE recommends Ultomiris for NHS use in patients with rare blood disorders Soliris (eculizumab) for at least three months and have evidence of response to this therapy. ... Clinical trial evidence has shown that treatment with Ultomiris in people with PNH is at least as clinically effective as Soliris and it is administered

FDA approves Apellis’ Empaveli for rare blood disease

FDA approves Apellis’ Empaveli for rare blood disease PEGASUS study results show Empaveli is better than Soliris at improving haemoglobin levels. ... In addition, 85% of Empaveli-treated patients were transfusion free over 16 weeks compared with 15% of Soliris-treated patients.

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