The Top Pharma List's top 50 pharmaceutical products by global sales ranking is compiled from GlobalData's pharmaceutical revenue figures. Zetia was produced by Merck & Co. and Bayer.
comparator drug Zetia (ezetimibe) from Merck &Co.
HIV drug Isentress (raltegravir) climbed 5 per cent to $410m, holding up fairly well despite increased competition from the likes of Gilead Sciences' elvitegravir, while sales of cholesterol drugs Zetia (ezetimibe) ... and Vytorin (ezetimibe and
Vytorin extension wins FDA approval. Merck &Co has been awarded marketing approval for Liptruzet, a new combination cholesterol treatment based on Zetia and generic atorvastatin. ... Sales of Zetia as a monotherapy reached $2.57bn last year, with Vytorin
insomnia drug suvorexant, ovarian cancer treatment vintafolide, and its combination of Zetia (ezetimibe) and atorvastatin for high cholesterol.
The debate has dampened demand for Vytorin and also ezetimibe monotherapy Zetia, which has had its own problems including a study which suggested the drug increased atherosclerotic plaque volumes in peripheral
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